Boldenone can be converted to estrogen but less so than testosterone, in addition, boldenone is metabolized to 1,4 dienedione which is a potent aromatase inhibitor. Boldenone is converted by 5-alpha reductase to 1-testosterone, a more potent steroid as well as to the 5-beta isomer which is thought to be an inactive metabolite. Binding to SHBG is much lower with boldenone than with testosterone meaning a larger free plasma concentration but a shorter half-life in plasma. There is little to no binding to progesterone or glucocorticoid receptors and no real data on the interaction of boldenone with the different enzyme systems.
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